I'm glad you brought that up because I have been thinking about my path in life. It's funny how you grow so much on the path, that you lose interest in the things you once felt sustained you. I know God has a bigger purpose for me. I always felt like there was something special that I would have to do in this life. When I kept trying to ignore or walk away from it, my life seemed to go haywire. It's like I had the worst luck. Nothing would go my way. I would try and try without succeeding. I then gave in to the calling. I knew it was a matter time. So, I decided to stop fighting it, and move in sync with it. Things are starting to pick up for me, especially since I realized some key issues I needed to resolve in my life. I see a brighter future up a ahead. I know it's all because of the realization I had, that I acted upon.
I agree, so many of us have strayed away from the divine plan. When you are following the divine plan things usually work out for you. When you stray away from it, or it is time for you to leave the old - you will find that things don't work for you anymore. In fact, you will actually develop massive resistance to going forward in the same direction (that is what is happening to me right now) and you could even develop depression and fatigue if you keep trying to go in the same direction.
Also, when you are off your path or need to leave a life you have been leading, like you have seen, it is almost like moving thru thick mud - nothing works out for you or works for you anymore. This is actually good - because it then forces you to go in a new, better and possibly even different direction than the one you were thinking of.
Life is about moving onward and upward and when one path is done, another will open up that is even more joyful and rewarding than the one you are currently on. So that is great you have all this insight!