Science and math is limited by definition, because it is based on an objective universe, which Steve has already bashed into our heads over and over that an objective universe doesn't exist
However, science can get close to explaining some spiritual concepts. Quantum mechanics, in particular Bohm's theory of implicate/explicate order, Morphogenetic/attractor fields, and Amit Goswami's Conciousness-based quantum mechanics model all show some promise in partially explaining Reality. Much of this was talked about in The Secret and What The Bleep, although in watered-down format.
Aaron's theories (
PATHS and Quantum Physics and
http://www.♥♥♥♥♥♥♥.org/library/loa-s...ty-diagram.pdf) seem to explain Reality the closest out of all the metaphysical/scientific models I've seen. And PATHS does work, which shows that this scientific model has practical validity.
However, in order to truly know God and experience spiritual truth directly, it is necessary to study pure spirituality, i.e. the Four Yogas, Advaita Vedanta, Buddhism, Zen, etc. I think science can help speed up the process (like PATHS has done for me), but ultimately it is only a supplement to actual spiritual work. Science will no longer exist when you die, but your soul and spiritual evolution will still be with you, so it is up to you what you want to focus on in this life
Use all the tools you can, but ultimately it is spiritual evolution that will get you to the Kingdom of Heaven, and Beyond.
Food for thought.