I don't have any firm belief about what happens when we die. But my lack of experience of anyone returning to tell me what happens afterwards leads me to believe that the process is irreversible.
That doesn't exclude the end of awareness at all levels (complete death, oblivion), or reincarnation, or Peter F. Hamilton's concept of the Beyond, what souls really are, and what it all really means. Hamilton's Night's Dawn series is a great illustration of the melding of science and spirituality, though being a sci-fi series the melding takes on scientific form. But again, that doesn't lesson the beauty (and possibility of horror) of spirituality.
But I don't think I'll find out until I die.
I could go on but I don't want to derail the thread