Pizza is loaded with damaged vegetable oil/oxidized cholesterol from the meat, Acrylamide ( baked caborhydrate ), commercial cheese, flour ( refined carb -> high blood sugar ), processed meat and etc. It basically contains all the human made poison (from plant and animal based ) designed to destroy your body system.
Eat non-overcooked/non fried "real food" ( Vegetables,fruit, whole grains, grass fed animal food, deep sea fish ) and exercise everyday you would be fine.
Exercise = the newly approved drug to fight off chronic diseases 