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Think of it this way. I read somewhere that average adult on the SAD diet carries around something like +10lbs of fecal matter (toxins) in their colon stuck to the walls of the colon.
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Just my personal opinion,
I think that this is a huge myth designed to sell colon cleansing supplements.
I've seen testimonials from nurses who work in clinics that do colonoscopies (looking inside your colon with a video cam) all day, and they've never seen any fecal matter stuck to the walls of anyone's colon.
Also, just watch Discovery Health, or TLC, etc. You'll eventually see a few colonoscopies yourself, and even in "unhealthy" people, you never see anything but normal tissue...
That is not being covered by fecal matter.
My personal opinion is that your body can clean itself, and you don't have a bunch of toxins stuck in your colon.
That's what the toilet is for.