 Isotretinoin or rosehip oil
I agree that isotretinoin is really effective - but it is a mainstream pharmaceutical so isn't at all natural.
The closest natural treatment is rosehip oil, which contains some close analogues. Neals Yard and Artful Teasing do products rich in rosehip oil in the UK. I would think that there is something along the same lines in the US.
The link between diet and acne has never been proved scientifically as far as I know, though the benefits of a natural diet are probably worth it even if it doesn't help with your spots.
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