I recently purchased "The Fifth Discipline" by Peter Senge - it's a good read, if you have not read it yet, do so.
Peter talked about having a personal vision. To him, a vision is an something concrete which you reach out for. And that something concrete should be all-encompassng - in other words, it should cover the social, emotional, family, personal, material... etc... aspects of life. It's from that one personal vision that you set out measurable goals in order to attain the VISION. Besides personal vision, he talked about several other facets of personal mastery which are enlightening and at the same time, realistic and plain truths in all of us. For instance, he talked about the facet of CREATIVE TENSION - knowing the gaps between the current reality of what you are and what you want to achieve; and you progress only when you push yourself to what you want to excel in. That, in retrospect, is CREATIVE TENSION.
So, if you ask me, setting one goal or goals, it should be having a clear personal vision, and then setting the GOALS to attain that PERSONAL VISION.
JT
Training, Engaging the Adult Learners